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KMID : 1134820070360091120
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Journal of the Korean Society of Food Science and Nutrition
2007 Volume.36 No. 9 p.1120 ~ p.1127
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Effects of Conjugated Double Bond Derivatives of Polyunsaturated Fatty Acid on Serum Lipids in Rats
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Kim So-Young
Kim Sung-Hee
Kim Gyeong-Eup
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Abstract
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This study was designed to examine the effects of n?6 PUFA rich corn oil, n?3 PUFA rich perilla oil and their conjugated double bond derivatives on serum lipids status in rats. Experimental diets containing lard (control), corn oil (CO), perilla oil (PO), conjugated double bond derivatives of n?6 PUFA rich corn oil (TCO) and n?3 PUFA rich perilla oil (TPO) at the level of 10% (w/w) were fed to male Sprague Dawley rats for 4 weeks. TCO was found to have three derivatives of linoleic acid and TPO had five derivatives of linolenic acid by GC. Serum total cholesterol levels were significantly lower in the all experimental groups than in the control group, and particularly, the lowest in TCO and TPO groups. HDL?cholesterol concentrations were a little higher in the all experimental groups than in the control group, and TCO and TPO groups were not significantly different from CO and PO groups. Serum LDL, LDL?cholesterol, chylomicron and triglyceride concentrations were significantly lower in the all experimental groups than in the control group, remarkably lower in TCO group and particularly, the lowest in the TPO group. Serum free cholesterol and cholesteryl ester concentrations were lower in TCO and TPO groups than in CO and PO groups. From the above research, TCO and TPO groups were effective on the improvement of the lipid compositions in serum and particularly, TPO group was the most effective on the improvement of serum lipids.
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KEYWORD
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corn oil (CO), perilla oil (PO), conjugated double bond derivatives of n-6 PUFA rich corn oil (TCO), conjugated double bond derivatives of n-3 PUFA rich perilla oil (TPO)
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